Photo: Kelly Defina / Getty Images Sport / Getty Images
The New Orleans Pelicans are 4-point underdogs against the Memphis Grizzlies in the season opener for both teams at FedExForum on Wednesday, October 22, 2025. The game tips at 8 p.m. ET on FDSSE, Gulf Coast Sports, WVUE, and Pelicans+.
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Grizzlies vs. Pelicans Predictions for Wednesday
Our computer projection model for this matchup calls for a final result of Grizzlies 125, Pelicans 109.
- Moneyline Pick: Grizzlies (-185)
- Total Pick: Under 236.5 (computer predicts 233.3 points)
- Pick ATS: Grizzlies (-4)
Recent Grizzlies vs. Pelicans Matchups
| Date | Favorite | Spread | Total | Favorite Moneyline | Underdog Moneyline | Result |
|---|---|---|---|---|---|---|
| 3/9/2025 | Grizzlies | -10.5 | 239.5 | -521 | +391 | 107-104 MEM |
| 1/24/2025 | Grizzlies | -9.5 | 242.5 | -442 | +341 | 139-126 MEM |
| 12/27/2024 | Grizzlies | -7.5 | 237.5 | -321 | +254 | 132-124 MEM |
| 11/29/2024 | Grizzlies | -12.5 | 232 | -813 | +562 | 120-109 MEM |
Grizzlies 2024-25 Betting Trends
- Memphis was 41-40-1 against the spread last season.
- Against the spread, as 4-point favorites or greater, the Grizzlies went 21-15 last season.
- Out of 82 Memphis games last season, 47 went over the total.
- The Grizzlies finished 39-13 in games they were listed as the moneyline favorite last season (winning 75% of those games).
- In games it played as a moneyline favorite with odds of -185 or shorter last year, Memphis finished with a record of 25-8 (75.8%).
Pelicans 2024-25 Betting Trends
- New Orleans won 34 games against the spread last year, while failing to cover or pushing 48 times.
- The Pelicans had an ATS record of 22-31 as underdogs of 4 points or more last season.
- A total of 45 of New Orleans' games last season went over the point total.
- The Pelicans were underdogs in 61 games last season and won nine (14.8%) of those contests.
- Last season, New Orleans won five of its 50 games, or 10%, when it was the underdog by at least +154 on the moneyline.
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Grizzlies vs. Pelicans Injury Report
Grizzlies
Grizzlies:
Zach Edey: Out (Ankle),
Brandon Clarke: Out (Knee),
Scotty Pippen Jr.: Out (Toe),
Ty Jerome: Out (Calf),
Vince Williams: Out (Heel)
Pelicans
Pelicans:
Kevon Looney: Out (Knee),
Dejounte Murray: Out (Leg),
Karlo Matkovic: Day-To-Day (Back)
Grizzlies vs. Pelicans Game Time and TV Channel
- Game day: Wednesday, October 22, 2025
- Game time: 8 p.m. ET
- TV channel: FDSSE, Gulf Coast Sports, WVUE, and Pelicans+
- Location: Memphis, Tennessee
- Arena: FedExForum
- Live stream: Watch this game on Fubo (Regional restrictions may apply)
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